1,3,3,5,5-五甲基环己胺
化合物
1,3,3,5,5-五甲基环己胺（英语：1,3,3,5,5-pentamethylcyclohexanamine，或称为Neramexane）是一种美金刚胺相关药物，分子式为C11H23N[1]，作为一种NMDA受体拮抗剂[2]，具有神经保护作用[3]。
 | |
| 临床资料 | |
|---|---|
| ATC码 |
|
| 识别信息 | |
| |
| CAS号 | 219810-59-0  |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.107.752 |
| 化学信息 | |
| 化学式 | C11H23N |
| 摩尔质量 | 169.31 g·mol−1 |
| 3D模型（JSmol） | |
| |
| |
参考文献
编辑- ^ Gilling K, Jatzke C, Wollenburg C, Vanejevs M, Kauss V, Jirgensons A, Parsons CG. A novel class of amino-alkylcyclohexanes as uncompetitive, fast, voltage-dependent, N-methyl-D-aspartate (NMDA) receptor antagonists--in vitro characterization. Journal of Neural Transmission. 2007, 114 (12): 1529–37. PMID 17728997. S2CID 8654883. doi:10.1007/s00702-007-0792-7.
- ^ Danysz W, Parsons CG, Jirgensons A, Kauss V, Tillner J. Amino-alkyl-cyclohexanes as a novel class of uncompetitive NMDA receptor antagonists. Current Pharmaceutical Design. 2002, 8 (10): 835–43. PMID 11945134. doi:10.2174/1381612024607117.
- ^ Danysz W, Parsons CG. Neuroprotective potential of ionotropic glutamate receptor antagonists. Neurotoxicity Research. March 2002, 4 (2): 119–26. PMID 12829411. S2CID 9413469. doi:10.1080/10298420290015872.