甘露聚糖结合凝集素

Mannose-binding lectin (protein C) 2, soluble
甘露糖结合凝集素（蛋白C）2，可溶
Mannose-binding lectin (protein C) 2, soluble; 甘露糖结合凝集素（蛋白C）2，可溶
	PDB rendering based on 1hup.
有效结构
PDB	直系同源检索：PDBe, RCSB
PDB查询代码列表
	1HUP
标识
代号	MBL2; COLEC1; HSMBPC; MBL; MBL2D; MBP; MBP-C; MBP1; MBPD
扩展标识	遗传学：154545 鼠基因：96924 同源基因：110436 ChEMBL: 1795113 GeneCards: MBL2 Gene
基因本体论描述
分子功能	· receptor binding; · protein binding; · mannose binding; · eukaryotic cell surface binding; · calcium-dependent protein binding; · bacterial cell surface binding;
细胞成分	· extracellular region; · collagen; · extracellular space;
生物过程	· complement activation, lectin pathway; · acute-phase response; · complement activation; · complement activation, classical pathway; · response to oxidative stress; · opsonization; · negative regulation of growth of symbiont in host; · innate immune response; · positive regulation of phagocytosis; · defense response to Gram-positive bacterium; · killing by host of symbiont cells;
	Sources: Amigo / QuickGO
RNA表达模式
	更多表达数据
直系同源体
物种	人类
Entrez	4153
Ensembl	ENSG00000165471
UniProt	P11226
mRNA序列	NM_000242
蛋白序列	NP_000233
基因位置	Chr 10:; 54.53 – 54.53 Mb
PubMed查询	[1]
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甘露聚糖结合凝集素（英语：Mannose-binding lectin，缩写MBL，也被称为甘露糖结合蛋白或甘露聚糖结合蛋白，英语：mannan-binding protein，缩写MBP）是一种在先天免疫系统中起作用的凝集素^[1]^[2]。

外部连接

^ Fraser IP, Koziel H, Ezekowitz RA. The serum mannose-binding protein and the macrophage mannose receptor are pattern recognition molecules that link innate and adaptive immunity.. Semin. Immunol. 1998, 10 (5): 363–72. PMID 9799711. doi:10.1006/smim.1998.0141.
^ Worthley DL, Bardy PG, Mullighan CG. Mannose-binding lectin: biology and clinical implications.. Internal medicine journal. 2005, 35 (9): 548–55. PMID 16105157. doi:10.1111/j.1445-5994.2005.00908.x.