2-氟-6-氯甲苯
化合物
2-氟-6-氯甲苯是一種有機化合物，化學式為C7H6ClF。它可由3-氯-2-甲基苯胺、亞硝酸鈉和氫氟酸為原料反應得到。[2]在鐵存在下，它和溴反應，可以得到2-氯-3-溴-6-氟甲苯。[3]在過氧化苯甲醯存在下，它和N-溴代丁二醯亞胺反應，可以得到2-氟-6-氯-α,α-二溴甲苯。[4]
| 2-氟-6-氯甲苯 | |
|---|---|
| |
| IUPAC名 1-chloro-3-fluoro-2-methylbenzene | |
| 別名 | 2-氯-6-氟甲苯 |
| 識別 | |
| CAS號 | 443-83-4 |
| PubChem | 9933 |
| SMILES |
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| InChI |
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| EINECS | 207-141-9 |
| 性質 | |
| 化學式 | C7H6ClF |
| 摩爾質量 | 144.57 g·mol−1 |
| 沸點 | 154 °C[1] |
| 危險性 | |
GHS危險性符號 
| |
| GHS提示詞 | 警告 |
| H-術語 | H226, H302, H312, H315, H332, H335 |
| P-術語 | P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P302+352, P303+361+353, P304+340 |
| 閃點 | 46 °C (115 °F) |
| 若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。 | |
參考文獻
編輯- ^ "PhysProp" data were obtained from Syracuse Research Corporation of Syracuse, New York (US). Retrieved from SciFinder. [2022-3-19].
- ^ Li, Xiao Yun; Zheng, Qiong; Yu, Peng; Huang, Chi; Jian, Li Duan; Peng, Jun Qing. A new synthetic route for preparation of 2-chloro-6-fluorobenzonitrile and 2-chloro-6-fluorobenzoic acid. Chinese Chemical Letters, 2004. 15 (8): 895-898. ISSN 1001-8417.
- ^ Nathalie Schlienger, Birgitte W. Lund, Jan Pawlas, Fabrizio Badalassi, Fabio Bertozzi, Rasmus Lewinsky, Alma Fejzic, Mikkel B. Thygesen, Ali Tabatabaei, Stefania Risso Bradley, Luis R. Gardell, Fabrice Piu, Roger Olsson. Synthesis, Structure−Activity Relationships, and Characterization of Novel Nonsteroidal and Selective Androgen Receptor Modulators. Journal of Medicinal Chemistry. 2009-11-26, 52 (22): 7186–7191 [2022-03-19]. ISSN 0022-2623. doi:10.1021/jm901149c. （原始內容存檔於2021-12-25） （英語）.
- ^ Kambappa Vinaya, Ganganahalli K. Chandrashekara, Prasanna D. Shivaramu. One-pot synthesis of 3,5-diaryl substituted-1,2,4-oxadiazoles using gem -dibromomethylarenes. Canadian Journal of Chemistry. 2019-09, 97 (9): 690–696 [2022-03-19]. ISSN 0008-4042. doi:10.1139/cjc-2018-0333 （英語）.