尼莫拉唑

化合物

尼莫拉唑INNnimorazole,开发代号:K-1900),分子式C9H14N4O3,是一种5-硝基咪唑抗寄生虫药[1],也用作頭頸癌药物[2][3]

尼莫拉唑
臨床資料
AHFS/Drugs.com国际药品名称
ATC碼
识别信息
  • 4-[2-(5-nitro-1H-imidazol-1-yl)ethyl]morpholine
CAS号6506-37-2
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.026.723 編輯維基數據鏈接
化学信息
化学式C9H14N4O3
摩尔质量226.24 g·mol−1
3D模型(JSmol英语JSmol
  • C1COCCN1CCN2C=NC=C2[N+](=O)[O-]
  • InChI=1S/C9H14N4O3/c14-13(15)9-7-10-8-12(9)2-1-11-3-5-16-6-4-11/h7-8H,1-6H2
  • Key:MDJFHRLTPRPZLY-UHFFFAOYSA-N

参考文献

编辑
  1. ^ Roy RB, Laird SM, Heasman L. Treatment of trichomoniasis in the female. A comparison of metronidazole and nimorazole. The British Journal of Venereal Diseases. August 1975, 51 (4): 281–4. PMC 1046566 . PMID 1098732. doi:10.1136/sti.51.4.281. 
  2. ^ Henk JM, Bishop K, Shepherd SF. Treatment of head and neck cancer with CHART and nimorazole: phase II study. Radiotherapy and Oncology. January 2003, 66 (1): 65–70. PMID 12559522. doi:10.1016/S0167-8140(02)00284-0 . 
  3. ^ Clinical trial number NCT01507467 for "IAEA-HypoX. Accelerated Radiotherapy With or Without Nimorazole in Squamous Cell Carcinoma of the Head and Neck" at ClinicalTrials.gov

外部链接

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