CD1a (C luster of D ifferentiation 1a )是身上的一種人類蛋白质 ,由基因「CD1A 」轉譯而成[ 3] 。
該蛋白屬於CD1蛋白家族 ,為一種穿膜醣蛋白。CD1a與β2-微球蛋白 共同構成的異源二聚體(heterodimers)稱為「CD1a複合體」(CD1a complex),在結構上類似MHC I分子 。兩者都具有抗原呈現 的能力,但CD1a主要呈現的是糖脂類 ,而MHC分子主要呈現的是多肽類 。人類身上的CD1家族基因共有五個,且都集中排列在1號染色體 上的某個區域[ 3] 。
在抽菸的病人身上,「CD1A 」在肺間質的表現會較為顯著[ 4] 。
^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000158477 - Ensembl , May 2017
^ Human PubMed Reference: . National Center for Biotechnology Information, U.S. National Library of Medicine.
^ 3.0 3.1 Entrez Gene: CD1A CD1a molecule .
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CD1A 引用了美国国家医学图书馆 提供的資料,这些資料属于公共领域 。