細胞色素b5

細胞色素b5（英語：Cytochrome b5）是一種存在於動物、植物、真菌以及紫色光養菌中遍及的電子傳遞血紅素蛋白。該細胞色素於微粒體及線粒體中的變體是與膜相結合的，而細菌、紅細胞以及其他動物組織中的卻是水溶性的。

細胞色素b5
結合了血紅素的大鼠細胞色素b5
識別
符號	CYB5A
替換符號	CYB5
Entrez	1528
HUGO	2570
OMIM	250790
PDB	1JEX
RefSeq	NM_001914
UniProt	P00167
其他資料
基因座	18 q23

細胞色素b5
鑑定
標誌	Cyt_B5
Pfam	PF00173（舊版）
InterPro	IPR001199
PROSITE	PDOC00170
現有可用的蛋白結構： Pfam 結構（舊版） / ECOD PDB RCSB PDB; PDBe; PDBj PDBsum 結構概要 PDB 1aqa, 1aw3, 1awp, 1axx, 1b5a, 1b5b, 1b5m, 1bfx, 1blv, 1cxy, 1cyo, 1do9, 1ehb, 1es1, 1eue, 1f03, 1f04, 1fcb, 1hko, 1i5u, 1i87, 1i8c, 1ib7, 1icc, 1iet, 1ieu, 1j03, 1j0q, 1jex, 1kbi, 1kbj, 1lco, 1ldc, 1lj0, 1lqx, 1lr6, 1ltd, 1m20, 1m2i, 1m2m, 1m59, 1mj4, 1mny, 1nx7, 1qcw, 1sh4, 1sox, 1sze, 1szf, 1szg, 1t0g, 1u9m, 1u9u, 1x3x, 2axx, 2i89, 2ibj, 2oz0

參考文獻

• Lederer, F. The cytochrome b₅-fold: an adaptable module. Biochimie. 1994, 76 (7): 674–692. PMID 7893819. doi:10.1016/0300-9084(94)90144-9. 
• Napier, J.A., Michaelson, L.V. and Sayanova, O. The role of cytochrome b₅ fusion desaturases in the synthesis of polyunsaturated fatty acids. Prostaglandins, Leukotrienes and Essential Fatty Acids. 2003, 68 (2): 135–143. PMID 12538077. doi:10.1016/S0952-3278(02)00263-6. 
• Rivera, M., Barillas-Mury, C., Christensen, K.A., Little, J.W., Wells, M.A. and Walker, F.A. Gene synthesis, bacterial expression, and ¹H NMR spectroscopic studies of the rat outer mitochondrial membrane cytochrome b₅. Biochemistry. 1992, 31 (48): 12233–12240. PMID 1333795. doi:10.1021/bi00163a037. 
• Schenkman, J.B. and Jansson, I. The many roles of cytochrome b₅. Pharmacol. Ther. 2003, 97 (2): 139–152. PMID 12559387. doi:10.1016/S0163-7258(02)00327-3. 

外部連結

• PDB 1B5A - Solution structure of rat cytochrome b₅ (form A)
• PDB 1B5B - Solution structure of rat cytochrome b₅ (form B)
• PDB 1CXY - X-ray structure of cytochrome b₅₅₈ from Ectothiorhodospira vacuolata
• OMIM 250790 - Methemoglobinemia due to deficiency of cytochrome b₅