炔孕酮
化合物
炔孕酮(英语:Ethisterone),也有称为乙炔睾酮(英语:ethinyltestosterone)、孕炔醇酮(英语:pregneninolone,商品名:Proluton C 或 Pranone等)是一种黄体制剂药物,过去被用于治疗一些妇科疾病,但现在已不再使用[3][4][5]。
临床资料 | |
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商品名 | Proluton C, Pranone, others |
其他名称 | Ethinyltestosterone; Ethynyltestosterone; Pregneninolone; Anhydrohydroxyprogesterone; Etisteron; Pregnin; Ethindrone |
给药途径 | 口服给药,口腔黏膜吸收[1] |
药物类别 | Progestin; Progestogen; Androgen; Anabolic steroid |
ATC码 | |
药物动力学数据 | |
代谢产物 | • 5α-双氢炔孕酮[2] |
识别信息 | |
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CAS号 | 434-03-7 |
PubChem CID | |
ChemSpider | |
UNII | |
ChEBI | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.006.452 |
化学信息 | |
化学式 | C21H28O2 |
摩尔质量 | 312.446 g/mol |
3D模型(JSmol) | |
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参考文献
编辑- ^ University of California (1868-1952). Hospital Formulary and Compendium of Useful Information. University of California Press. 1952: 49–. GGKEY:2UAAZRZ5LN0.
- ^ Lemus AE, Enríquez J, García GA, Grillasca I, Pérez-Palacios G. 5alpha-reduction of norethisterone enhances its binding affinity for androgen receptors but diminishes its androgenic potency. J. Steroid Biochem. Mol. Biol. 1997, 60 (1–2): 121–9. PMID 9182866. doi:10.1016/s0960-0760(96)00172-0.
- ^ Swyer GI. Oral Hormonal Therapy for Menstrual Disorders. Br Med J. 1950, 1 (4654): 626–34. PMC 2037145 . PMID 20787798. doi:10.1136/bmj.1.4654.626.
- ^ Dr. Ian Morton; I.K. Morton; Judith M. Hall. Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. 31 October 1999: 115–. ISBN 978-0-7514-0499-9.
- ^ 存档副本. [2019-06-24]. (原始内容存档于2019-06-24).