十一烯酸睪酮

**十一烯酸睪酮**
臨床資料
商品名（英語：Drug nomenclature）	Durasteron、Triolandren
其他名稱	TUe、睪酮十一烯酸酯
給藥途徑	靜脈注射
藥物類別（英語：Drug class）	雄激素、合成代謝類固醇、雄激素酯
識別資訊
	IUPAC命名法 [(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] undec-10-enoate; ;
CAS號	29430-26-0
PubChem CID	9846790;
ChemSpider	21229627;
UNII	KU65V22IOU;
CompTox Dashboard（英語：CompTox Chemicals Dashboard） (EPA)	DTXSID10951953 ;
ECHA InfoCard	100.045.099
化學資訊
化學式	C30H46O3
摩爾質量	454.70 g·mol−1
3D模型（JSmol（英語：JSmol））	交互式圖像;
	SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2OC(=O)CCCCCCCCC=C)CCC4=CC(=O)CC[C@]34C;
	InChI InChI=1S/C30H46O3/c1-4-5-6-7-8-9-10-11-12-28(32)33-27-16-15-25-24-14-13-22-21-23(31)17-19-29(22,2)26(24)18-20-30(25,27)3/h4,21,24-27H,1,5-20H2,2-3H3/t24-,25-,26-,27-,29-,30-/m0/s1; Key:PBFYIQCFOZXSKC-CNQKSJKFSA-N;

十一烯酸睪酮，縮寫TUe，是一種雄激素/合成代謝類固醇藥物和雄激素酯，已不再上市。^[1]^[2]^[3]它是Durasteron和Triolandren的成分，這兩種藥物是長效的睪酮酯油溶液混合物，通過肌肉注射給藥。^[4]^[5]^[6]^[7]

參見

參考資料

^ Shapiro S, Weinburg K, Freedman L. Notes - Long-Acting Androgens. The Journal of Organic Chemistry. 1956, 21 (11): 1300–1302. ISSN 0022-3263. doi:10.1021/jo01117a602.
^ Gould D, Finckenor L, Hershberg EB, Cassidy J, Perlman PL. Long-acting Testosterone Esters. Some Considerations on their Biological Utilization1. Journal of the American Chemical Society. 1957, 79 (16): 4472–4475. ISSN 0002-7863. doi:10.1021/ja01573a061.
^ US 2855341,Meier, R; A Wettstein & E Lang,「Testosterone compositions」,發表於1958-10-07,指定於Ciba pharmaceutical Products, Inc.
^ Schuermann H, Doepfmer R. Fertilitätsstörungen beim Manne. Springer-Verlag. 1960: 260–. ISBN 978-3-642-94784-1.
^ Ufer J. Hormontherapie in der Frauenheilkunde: Grundlagen und Praxis. Gruyter. 1960: 153. ISBN 9783111138770.
^ Aakvaag A, Vogt JH. Plasma testosterone values in different forms of testosterone treatment. Acta Endocrinologica. March 1969, 60 (3): 537–542. PMID 5395873. doi:10.1530/acta.0.0600537. Triolandren®, for intramuscular use, kindly supplied by Ciba, Basel, through Kobro 8c Co., Oslo, containing three different testosterone esters, in the following amounts of testosterone equivalents per ml oil: propionate 20 mg; valerate 80 mg; undecylenate 150 mg.
^ Zachmann M, Prader A. Anabolic and androgenic effect of testosterone in sexually immature boys and its dependency on growth hormone. The Journal of Clinical Endocrinology and Metabolism. January 1970, 30 (1): 85–95. PMID 4311616. doi:10.1210/jcem-30-1-85. Triolandren, CIBA; 250 mg of this preparation contains 20 mg of testosterone propionate, 80 mg of testosterone-n-valerianate, and 150 mg of testosterone undecylenate—250 mg thus contains 173.8 mg of testosterone; the remaining 76.2 mg consists of the ester components [...]

[ShapiroWeinburg1956-1] Shapiro S, Weinburg K, Freedman L. Notes - Long-Acting Androgens. The Journal of Organic Chemistry. 1956, 21 (11): 1300–1302. ISSN 0022-3263. doi:10.1021/jo01117a602.

[GouldFinckenor1957-2] Gould D, Finckenor L, Hershberg EB, Cassidy J, Perlman PL. Long-acting Testosterone Esters. Some Considerations on their Biological Utilization1. Journal of the American Chemical Society. 1957, 79 (16): 4472–4475. ISSN 0002-7863. doi:10.1021/ja01573a061.

[US2855341A-3] US 2855341,Meier, R; A Wettstein & E Lang,「Testosterone compositions」,發表於1958-10-07,指定於Ciba pharmaceutical Products, Inc.

[SchuermannDoepfmer1960-4] Schuermann H, Doepfmer R. Fertilitätsstörungen beim Manne. Springer-Verlag. 1960: 260–. ISBN 978-3-642-94784-1.

[Ufer1960-5] Ufer J. Hormontherapie in der Frauenheilkunde: Grundlagen und Praxis. Gruyter. 1960: 153. ISBN 9783111138770.

[pmid5395873-6] Aakvaag A, Vogt JH. Plasma testosterone values in different forms of testosterone treatment. Acta Endocrinologica. March 1969, 60 (3): 537–542. PMID 5395873. doi:10.1530/acta.0.0600537. Triolandren®, for intramuscular use, kindly supplied by Ciba, Basel, through Kobro 8c Co., Oslo, containing three different testosterone esters, in the following amounts of testosterone equivalents per ml oil: propionate 20 mg; valerate 80 mg; undecylenate 150 mg.

[ZachmannPrader1970-7] Zachmann M, Prader A. Anabolic and androgenic effect of testosterone in sexually immature boys and its dependency on growth hormone. The Journal of Clinical Endocrinology and Metabolism. January 1970, 30 (1): 85–95. PMID 4311616. doi:10.1210/jcem-30-1-85. Triolandren, CIBA; 250 mg of this preparation contains 20 mg of testosterone propionate, 80 mg of testosterone-n-valerianate, and 150 mg of testosterone undecylenate—250 mg thus contains 173.8 mg of testosterone; the remaining 76.2 mg consists of the ester components [...]

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